ELM - instance MOD_CDK_SPK_2 in sequence P26358 at position 151

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI003236	P26358 DNMT1 DNMT1_HUMAN	151	156	DGEAKPEPSPSPRITRKSTR	TP	---	Homo sapiens (Human)	1616

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0586	inhibitor		Lavoie,2011	support	certain
experimental	MI:0943	detection by mass spectrometry	in vivo/in vitro	Lavoie,2011	support	certain	InteractionDetection
experimental	MI:0113	western blot	in vitro	Lavoie,2011	support	certain	ParticipantIdentification FeatureDetection
experimental	MI:0421	identification by antibody		Lavoie,2011	support	certain	ParticipantIdentification
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Lavoie,2011	support	certain	FeatureDetection
experimental	MI:0424	protein kinase assay	in vitro	Lavoie,2011	support	certain	InteractionDetection
experimental	MI:0424	protein kinase assay	in vivo	Lavoie,2011	support	certain	InteractionDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Notes
(P06493) CDK1_HUMAN	PF00069 (Pkinase) Protein kinase domain	4	287	[mitab][xml]
(P24941) CDK2_HUMAN	PF00069 (Pkinase) Protein kinase domain	4	286	[mitab][xml]
(Q00535) CDK5_HUMAN	PF00069 (Pkinase) Protein kinase domain	4	286	[mitab][xml]

Pathways

KEGG: The sequence P26358 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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