Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003227 | P49768 PSEN1 PSN1_HUMAN |
351 | 358 | DSHLGPHRSTPESRAAVQEL | TP | --- | Homo sapiens (Human) | 467 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0517 | radiolabel | in vitro | Lau,2002 | support | certain | |
experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Lau,2002 | support | certain | FeatureDetection |
experimental | MI:0424 | protein kinase assay | in vitro | Lau,2002 | support | certain | InteractionDetection |
experimental | MI:0424 | protein kinase assay | in vivo | Lau,2002 | support | certain | InteractionDetection |
experimental | MI:0413 | electrophoretic mobility shift assay | Lau,2002 | support | certain | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q00535) CDK5_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
4 | 286 | [mitab][xml] |
Pathways
KEGG: The sequence P49768 is implicated in the following 6 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement