| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length | 
|---|---|---|---|---|---|---|---|---|
| ELMI003214 |  P39689 Cdkn1a CDN1A_MOUSE  | 
        75 | 82 | SLGLPKVYLSPGSRSRDDLG | TP | --- | Mus musculus (House mouse) | 159 | 
  Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes | 
|---|---|---|---|---|---|---|---|
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Hodeify,2011 | support | certain | FeatureDetection | 
| experimental | MI:0943 | detection by mass spectrometry | in vivo/in vitro | Hodeify,2011 | support | certain | InteractionDetection | 
| experimental | MI:0807 | comigration in gel electrophoresis | in vitro | Hodeify,2011 | support | certain | InteractionDetection | 
  Interactions 
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes | 
|---|---|---|---|---|---|
| (P24941) CDK2_HUMAN |  PF00069
                  (Pkinase) 
                  Protein kinase domain  | 
             4 | 286 | [mitab][xml] | 
  Pathways 
- Basal cell carcinoma
 - Bladder cancer
 - Breast cancer
 - Cell cycle
 - Cellular senescence
 - Chronic myeloid leukemia
 - Colorectal cancer
 - Cushing syndrome
 - Endocrine resistance
 - Endometrial cancer
 - Epstein Barr virus infection
 - ErbB signaling pathway
 - FoxO signaling pathway
 - Gastric cancer
 - Glioma
 - HIF 1 signaling pathway
 - Hepatitis B
 - Hepatitis C
 - Hepatocellular carcinoma
 - Human T cell leukemia virus 1 infection
 - Human cytomegalovirus infection
 - Human papillomavirus infection
 - JAK STAT signaling pathway
 - Kaposi sarcoma associated herpesvirus infection
 - Melanoma
 - MicroRNAs in cancer
 - Non small cell lung cancer
 - Oxytocin signaling pathway
 - PI3K Akt signaling pathway
 - Pancreatic cancer
 - Parathyroid hormone synthesis, secretion and action
 - Pathways in cancer
 - Platinum drug resistance
 - Prostate cancer
 - Proteoglycans in cancer
 - Renal cell carcinoma
 - Small cell lung cancer
 - Thyroid cancer
 - Transcriptional misregulation in cancer
 - Viral carcinogenesis
 - p53 signaling pathway
 
    
        Please cite: 
            ELM-the Eukaryotic Linear Motif resource-2024 update.
        
    (PMID:37962385)
    
    
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
