The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003190 Q9JM54 Pmaip1
APR_MOUSE
70 86 ADLKDECAQLRRIGDKVNLR TP --- Mus musculus (House mouse) 103

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Day,2008 support certain FeatureDetection
experimental MI:0084 phage display Day,2008 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Day,2008 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Day,2008 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Czabotar,2007 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Czabotar,2007 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q07820) MCL1_HUMAN PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
213 312 0.0019/0.0019 [mitab][xml]

o  Pathways

KEGG: The sequence Q9JM54 is implicated in the following 7 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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