Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003145 | P30279 CCND2 CCND2_HUMAN |
2 | 17 | MELLCHEVDPVRRAVRDRNL | TP | --- | Homo sapiens (Human) | 289 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Ewen,1993 | support | certain | |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Kato,1993 | support | likely | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Ewen,1993 | support | likely | FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P06400) RB_HUMAN | PF01857
(RB_B)
Retinoblastoma-associated protein B domain |
646 | 765 | [mitab][xml] |
Pathways
KEGG: The sequence P30279 is implicated in the following 19 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Cell cycle
- Cellular senescence
- Epstein Barr virus infection
- Focal adhesion
- FoxO signaling pathway
- Hedgehog signaling pathway
- Hippo signaling pathway
- Human T cell leukemia virus 1 infection
- Human papillomavirus infection
- JAK STAT signaling pathway
- Measles
- MicroRNAs in cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Prolactin signaling pathway
- Transcriptional misregulation in cancer
- Viral carcinogenesis
- Wnt signaling pathway
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement