The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003111 P03129 E7
VE7_HPV16
21 37 TDLYCYEQLNDSSEEEDEID TP 1GUX  
pdb:1GUX
Human papillomavirus type 16 98

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0905 amplified luminescent proximity homogeneous assay Putta,2022 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Putta,2022 support certain InteractionDetection
experimental MI:0113 western blot in vitro James,2021 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro James,2021 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Dong,2001 support certain FeatureDetection
experimental MI:0892 solid phase assay in vitro Dong,2001 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Chemes,2010 support certain InteractionDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Chemes,2010 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Phelps,1992 support certain FeatureDetection
experimental MI:0053 fluorescence polarization spectroscopy in vitro Chemes,2011 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Singh,2005 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Lee,1998 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Lee,1998 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 0.06/0.06 [mitab][xml]
(P28749) RBL1_HUMAN IPR002719 (Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno...
787 943 0.1/0.1 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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