The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003085 Q2TAL5 SMTNL2
SMTL2_HUMAN
184 190 PDPPRPRPVSLSLRLPHQPV TP --- Homo sapiens (Human) 461

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Gordon,2013 support certain
experimental MI:0405 competition binding in vitro Gordon,2013 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Gordon,2013 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Gordon,2013 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P45983) MK08_HUMAN PF00069 (Pkinase)
Protein kinase domain
26 321 [mitab][xml]
(P45984) MK09_HUMAN PF00069 (Pkinase)
Protein kinase domain
26 321 [mitab][xml]
(P53779) MK10_HUMAN PF00069 (Pkinase)
Protein kinase domain
64 359 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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