Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003079 | P35570 Irs1 IRS1_RAT |
852 | 858 | TNSRLARPTRLSLGDPKAST | TP | --- | Rattus norvegicus (Norway rat) | 1235 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Lee,2003 | support | certain | InteractionDetection |
experimental | MI:0405 | competition binding | in vitro | Lee,2003 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Lee,2003 | support | certain | FeatureDetection |
Pathways
KEGG: The sequence P35570 is implicated in the following 20 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AMPK signaling pathway
- Adipocytokine signaling pathway
- Aldosterone regulated sodium reabsorption
- Alzheimer disease
- Autophagy animal
- Diabetic cardiomyopathy
- FoxO signaling pathway
- Growth hormone synthesis, secretion and action
- Insulin resistance
- Insulin signaling pathway
- Longevity regulating pathway
- Longevity regulating pathway multiple species
- MicroRNAs in cancer
- Neurotrophin signaling pathway
- Non alcoholic fatty liver disease
- PI3K Akt signaling pathway
- Regulation of lipolysis in adipocytes
- Type II diabetes mellitus
- cGMP PKG signaling pathway
- mTOR signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement