| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI002998 | O35147 Bad BAD_RAT |
134 | 139 | ELSPFRGRSRSAPPNLWAAQ | TP | --- | Rattus norvegicus (Norway rat) | 205 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0018 | two hybrid | in vivo | Hsu,1997 | support | certain | InteractionDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000105:
Phosphorylation of S137 by RAC-alpha serine/threonine-protein kinase (Akt1) in the 14-3-3-binding motif of Bcl2 antagonist of cell death (Bad) induces binding to the 14-3-3 protein beta/alpha (YWHAB) protein. This interaction inhibits the pro-apoptotic activity of Bcl2 antagonist of cell death (Bad).
Pathways
- Acute myeloid leukemia
- Alzheimer disease
- Amyotrophic lateral sclerosis
- Apoptosis
- Autophagy animal
- Chemical carcinogenesis reactive oxygen species
- Chemical carcinogenesis receptor activation
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocrine resistance
- Endometrial cancer
- ErbB signaling pathway
- Focal adhesion
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Herpes simplex virus 1 infection
- Human immunodeficiency virus 1 infection
- Human papillomavirus infection
- Insulin signaling pathway
- Lipid and atherosclerosis
- Measles
- Melanoma
- Neurotrophin signaling pathway
- Non small cell lung cancer
- PI3K Akt signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Pathways of neurodegeneration multiple diseases
- Platinum drug resistance
- Prion disease
- Prostate cancer
- Ras signaling pathway
- Renal cell carcinoma
- Thyroid hormone signaling pathway
- Toxoplasmosis
- Tuberculosis
- VEGF signaling pathway
- Viral carcinogenesis
- cAMP signaling pathway
- cGMP PKG signaling pathway
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement