| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI002989 | Q02156 PRKCE KPCE_HUMAN |
343 | 348 | SSPSEEDRSKSAPTSPCDQE | TP |
2WH0 |
Homo sapiens (Human) | 737 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0091 | chromatography technology | in vitro | Kostelecky,2009 | support | certain | InteractionDetection |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Kostelecky,2009 | support | certain | InteractionDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Kostelecky,2009 | support | certain | InteractionDetection FeatureDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000353:
Phosphorylation of two 14-3-3-binding motifs in Protein kinase C epsilon type (PRKCE) induces high-avidity binding to dimeric 14-3-3 protein zeta/delta (YWHAZ).
Pathways
- AGE RAGE signaling pathway in diabetic complications
- Aldosterone synthesis and secretion
- Apelin signaling pathway
- Fc gamma R mediated phagocytosis
- Inflammatory mediator regulation of TRP channels
- Insulin resistance
- MicroRNAs in cancer
- Shigellosis
- Sphingolipid signaling pathway
- Tight junction
- Type II diabetes mellitus
- Vascular smooth muscle contraction
- cGMP PKG signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement