The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002901 P61081 UBE2M
UBC12_HUMAN
1 4 MIKLFSLKQQKKEEESAGGT TP --- Homo sapiens (Human) 183

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0586 inhibitor Scott,2011 support certain
experimental MI:0065 isothermal titration calorimetry in vitro Scott,2011 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Scott,2011 support certain InteractionDetection FeatureDetection
experimental MI:0068 mass detection of residue modification in vitro Scott,2011 support certain FeatureDetection
experimental MI:0586 inhibitor Monda,2013 support certain
experimental MI:0065 isothermal titration calorimetry in vitro Monda,2013 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Monda,2013 support certain InteractionDetection FeatureDetection
experimental MI:0068 mass detection of residue modification in vitro Monda,2013 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q96GG9) DCNL1_HUMAN PF03556 (Cullin_binding)
Cullin binding
136 247 2.0/2.0 [mitab][xml]
(Q6PH85) DCNL2_HUMAN PF03556 (Cullin_binding)
Cullin binding
136 247 1.8/1.8 [mitab][xml]

o  Pathways

KEGG: The sequence P61081 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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