The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002831 Q64337 Sqstm1
SQSTM_MOUSE
349 354 HLSSKEVDPSTGELQSLQMP TP 3ADE  
Mus musculus (House mouse) 442

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Komatsu,2010 support certain
experimental MI:0405 competition binding in vitro Komatsu,2010 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Komatsu,2010 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Komatsu,2010 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Komatsu,2010 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Komatsu,2010 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9Z2X8) KEAP1_MOUSE PF01344 (Kelch_1)
Kelch motif
[mitab][xml]

o  Pathways

KEGG: The sequence Q64337 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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