The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002695 O43516 WIPF1
WIPF1_HUMAN
451 461 EDEWESRFYFHPISDLPPPE TP --- Homo sapiens (Human) 503

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Zettl,2002 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Zettl,2002 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Zettl,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O08816) WASL_RAT PF00568 (WH1)
WH1 domain
28 135 [mitab][xml]

o  Pathways

KEGG: The sequence O43516 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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