The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002693 Q6VAB6 KSR2
KSR2_HUMAN
393 396 EANFSANTLSVPRWSPQIPR TP --- Homo sapiens (Human) 950

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0900 p8 filamentous phage display Wigington,2020 support likely InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Wigington,2020 support likely InteractionDetection
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Dougherty,2009 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Dougherty,2009 support certain FeatureDetection
experimental MI:0403 colocalization in vitro Dougherty,2009 support certain
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Dougherty,2009 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P63098) CANB1_HUMAN PF13499 (EF_hand_7)
EF-hand domain pair
[mitab][xml]
(Q08209) PP2BA_HUMAN PF00149 (Metallophos)
Calcineurin-like phosphoesterase
83 285 [mitab][xml]

o  Pathways

KEGG: The sequence Q6VAB6 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org