The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
LIG_EF_ALG2_ABM_1

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002651 Q8WUM4 PDCD6IP
PDC6I_HUMAN 		802 810 QAQGPPYPTYPGYPGYCQMP TP 2ZNE  
Homo sapiens (Human) 868

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Suzuki,2008 support certain
experimental MI:0018 two hybrid in vivo Vito,1999 support certain InteractionDetection
experimental MI:0663 confocal microscopy in vivo/in vitro Vito,1999 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Vito,1999 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro Vito,1999 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Okumura,2013 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Suzuki,2009 support certain FeatureDetection
experimental MI:0018 two hybrid in vivo Missotten,1999 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Missotten,1999 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Missotten,1999 support certain FeatureDetection
experimental MI:0047 far western blotting in vitro Shibata,2004 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Shibata,2004 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Shibata,2004 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Shibata,2004 support certain FeatureDetection
experimental MI:0047 far western blotting in vitro Suzuki,2008 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Suzuki,2008 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Suzuki,2008 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Suzuki,2008 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O75340) PDCD6_HUMAN SM00054 (EFh)
EF-hand, calcium binding motif 		27 55 [mitab][xml]
(O75340) PDCD6_HUMAN SM00054 (EFh)
EF-hand, calcium binding motif 		64 92 [mitab][xml]
(O75340) PDCD6_HUMAN SM00054 (EFh)
EF-hand, calcium binding motif 		94 122 [mitab][xml]
(O75340) PDCD6_HUMAN SM00054 (EFh)
EF-hand, calcium binding motif 		130 158 [mitab][xml]
(O75340) PDCD6_HUMAN SM00054 (EFh)
EF-hand, calcium binding motif 		160 190 [mitab][xml]
(P12815) PDCD6_MOUSE SM00054 (EFh)
EF-hand, calcium binding motif 		27 55 [mitab][xml]
(P12815) PDCD6_MOUSE SM00054 (EFh)
EF-hand, calcium binding motif 		64 92 [mitab][xml]
(P12815) PDCD6_MOUSE SM00054 (EFh)
EF-hand, calcium binding motif 		94 122 [mitab][xml]
(P12815) PDCD6_MOUSE SM00054 (EFh)
EF-hand, calcium binding motif 		130 158 [mitab][xml]
(P12815) PDCD6_MOUSE SM00054 (EFh)
EF-hand, calcium binding motif 		160 190 [mitab][xml]

o  Pathways

KEGG: The sequence Q8WUM4 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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