The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002627 P10071 GLI3
GLI3_HUMAN
333 340 SSSASGSYGHLSASAISPAL TP 4BLD  
pdb:4BLD
Homo sapiens (Human) 1580

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Cherry,2013 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9UMX1) SUFU_HUMAN PF05076 (SUFU)
Suppressor of fused protein (SUFU)
63 242 [mitab][xml]
(Q9UMX1) SUFU_HUMAN PF12470 (SUFU_C)
Suppressor of Fused Gli/Ci N terminal binding domain
252 473 [mitab][xml]

o  Pathways

KEGG: The sequence P10071 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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