Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002557 | P49815 TSC2 TSC2_HUMAN |
1457 | 1465 | SPSGLRPRGYTISDSAPSRR | TP | --- | Homo sapiens (Human) | 1807 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0424 | protein kinase assay | in vitro | Huang,2008 | support | likely | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P31749) AKT1_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
150 | 408 | [mitab][xml] |
Pathways
KEGG: The sequence P49815 is implicated in the following 15 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AMPK signaling pathway
- Autophagy animal
- Cellular senescence
- Choline metabolism in cancer
- Herpes simplex virus 1 infection
- Human cytomegalovirus infection
- Human papillomavirus infection
- Insulin signaling pathway
- Longevity regulating pathway
- PI3K Akt signaling pathway
- Phospholipase D signaling pathway
- Thermogenesis
- Thyroid hormone signaling pathway
- mTOR signaling pathway
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement