The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002556 P49815 TSC2
TSC2_HUMAN
1127 1135 RGARDRVRSMSGGHGLRVGA TP --- Homo sapiens (Human) 1807

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0424 protein kinase assay in vitro Huang,2008 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P31749) AKT1_HUMAN PF00069 (Pkinase)
Protein kinase domain
150 408 [mitab][xml]

o  Pathways

KEGG: The sequence P49815 is implicated in the following 15 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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