ELM - instance DEG_SCF_COI1_1 in sequence B2XVS2 at position 251

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI002519	B2XVS2 Jasmonate ZIM-domain protein 3 B2XVS2_SOLLC	251	268	PQARKASLARFLEKRKERVM	TP	---	Solanum lycopersicum (Tomato)	306

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0096	pull down	in vivo/in vitro		support	likely	InteractionDetection
experimental	MI:0521	his tag	in vivo/in vitro/in silico	Katsir,2008	support	likely
experimental	MI:0074	mutation analysis	in vivo/in vitro	Katsir,2008	support	likely	FeatureDetection

Switches

This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

SWTI000723:

Binding of to Coi1, an F-box substrate recognition subunit of the SCF E3 ubiquitin ligase, depends on binding of the plant hormone jasmonate to COI1, as this pre-assembled complex provides a composite binding site for the degron motif in the JAZ protein. Subsequent ubiquitylation of the JAZ protein by the SCF targets this transcriptional repressor for proteasomal degradation, a pre-requisite for the transcriptional response to jasmonate.

Pathways

KEGG: The sequence B2XVS2 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)

Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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