| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length | 
|---|---|---|---|---|---|---|---|---|
| ELMI002460 |  Q16665 HIF1A HIF1A_HUMAN  | 
        531 | 534 | VDSDMVNEFKLELVEKLFAE | TN | --- | Homo sapiens (Human) | 826 | 
  Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes | 
|---|---|---|---|---|---|---|---|
| experimental | MI:1008 | sumoylase assay | Berta,2007 | contradict | likely | InteractionDetection | |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Berta,2007 | contradict | likely | FeatureDetection | 
| experimental | MI:1008 | sumoylase assay | Bae,2004 | contradict | likely | InteractionDetection | |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Bae,2004 | contradict | likely | FeatureDetection | 
  Pathways 
- Autophagy animal
 - Central carbon metabolism in cancer
 - Chemical carcinogenesis reactive oxygen species
 - Choline metabolism in cancer
 - HIF 1 signaling pathway
 - Kaposi sarcoma associated herpesvirus infection
 - Mitophagy animal
 - PD L1 expression and PD 1 checkpoint pathway in cancer
 - Pathways in cancer
 - Proteoglycans in cancer
 - Renal cell carcinoma
 - Th17 cell differentiation
 - Thyroid hormone signaling pathway
 
    
        Please cite: 
            ELM-the Eukaryotic Linear Motif resource-2024 update.
        
    (PMID:37962385)
    
    
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
