The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002453 P17181 IFNAR1
INAR1_HUMAN
534 539 YSSQTSQDSGNYSNEDESES TP --- Homo sapiens (Human) 557

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0517 radiolabel in vitro Kumar,2004 support certain
experimental MI:0997 ubiquitinase assay in vitro Kumar,2004 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Kumar,2004 support certain InteractionDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Kumar,2004 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Kumar,2004 support certain FeatureDetection
experimental MI:0997 ubiquitinase assay in vitro Kumar,2003 support certain InteractionDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Kumar,2003 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Kumar,2003 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Kumar,2003 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9UKB1) FBW1B_HUMAN PF00400 (WD40)
WD domain, G-beta repeat
[mitab][xml]

o  Pathways

KEGG: The sequence P17181 is implicated in the following 18 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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