The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002209 P02751 FN1
FINC_HUMAN
1432 1434 YVVSIVALNGREESPLLIGQ TP --- Homo sapiens (Human) 2386

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0004 affinity chromatography technology in vivo/in vitro Busk,1992 support certain InteractionDetection
experimental MI:0086 polyclonal antibody in vitro Smith,1990 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Smith,1990 support certain InteractionDetection
experimental MI:0113 western blot in vitro Smith,1990 support certain ParticipantIdentification FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06756) ITAV_HUMAN PF08441 (Integrin_alpha2)
Integrin alpha
467 914 [mitab][xml]
(P06756) ITAV_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
[mitab][xml]
(P18084) ITB5_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
35 463 [mitab][xml]
(P18564) ITB6_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
30 456 [mitab][xml]

o  Pathways

KEGG: The sequence P02751 is implicated in the following 12 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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