| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length | 
|---|---|---|---|---|---|---|---|---|
| ELMI002208 |  P02751 FN1 FINC_HUMAN  | 
        501 | 503 | MMRCTCVGNGRGEWTCIAYS | TP | --- | Homo sapiens (Human) | 2386 | 
  Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes | 
|---|---|---|---|---|---|---|---|
| experimental | MI:0004 | affinity chromatography technology | in vivo/in vitro | Busk,1992 | support | certain | InteractionDetection | 
| experimental | MI:0086 | polyclonal antibody | in vitro | Smith,1990 | support | certain | ParticipantIdentification FeatureDetection | 
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Smith,1990 | support | certain | InteractionDetection | 
| experimental | MI:0113 | western blot | in vitro | Smith,1990 | support | certain | ParticipantIdentification FeatureDetection | 
| experimental | MI:0077 | nuclear magnetic resonance | in vitro | Spitaleri,2008 | support | certain | InteractionDetection FeatureDetection | 
  Interactions 
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes | 
|---|---|---|---|---|---|
| (P06756) ITAV_HUMAN |  PF08441
                  (Integrin_alpha2) 
                  Integrin alpha  | 
             467 | 914 | [mitab][xml] | |
| (P06756) ITAV_HUMAN |  PF01839
                  (FG-GAP) 
                  FG-GAP repeat  | 
             [mitab][xml] | |||
| (P05106) ITB3_HUMAN |  PF00362
                  (Integrin_beta) 
                  Integrin, beta chain  | 
             38 | 461 | [mitab][xml] | |
| (P18084) ITB5_HUMAN |  PF00362
                  (Integrin_beta) 
                  Integrin, beta chain  | 
             35 | 463 | [mitab][xml] | |
| (P18564) ITB6_HUMAN |  PF00362
                  (Integrin_beta) 
                  Integrin, beta chain  | 
             30 | 456 | [mitab][xml] | 
  Pathways 
- AGE RAGE signaling pathway in diabetic complications
 - Amoebiasis
 - Bacterial invasion of epithelial cells
 - ECM receptor interaction
 - Focal adhesion
 - Human papillomavirus infection
 - PI3K Akt signaling pathway
 - Pathways in cancer
 - Proteoglycans in cancer
 - Regulation of actin cytoskeleton
 - Small cell lung cancer
 - Yersinia infection
 
    
        Please cite: 
            ELM-the Eukaryotic Linear Motif resource-2024 update.
        
    (PMID:37962385)
    
    
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
