Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002070 | Q9P0K1 ADAM22 ADA22_HUMAN |
851 | 854 | KKKIRGKRFRPRSNSTETLS | TP | --- | Homo sapiens (Human) | 906 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0051 | fluorescence technology | Godde,2006 | support | likely | InteractionDetection | |
experimental | MI:0403 | colocalization | in vitro | Godde,2006 | support | likely | |
experimental | MI:0101 | sequence based prediction | in silico | Godde,2006 | support | likely | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Godde,2006 | support | likely | FeatureDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000317:
Phosphorylation-induced binding of dimeric 14-3-3 protein beta/alpha (YWHAB) to Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22) blocks ER retention motifs in Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22) and regulates transport of this protein to the membrane.
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement