| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI002032 | Q05397 PTK2 FAK1_HUMAN |
907 | 912 | EGVKLQPQEISPPPTANLDR | TP | --- | Homo sapiens (Human) | 1052 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Zheng,2009 | support | certain | |
| experimental | MI:0017 | classical fluorescence spectroscopy | in vitro | Zheng,2009 | support | certain | InteractionDetection |
| experimental | MI:0113 | western blot | in vitro | Zheng,2009 | support | certain | ParticipantIdentification FeatureDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Zheng,2009 | support | certain | FeatureDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000074:
Phosphorylation of S910 in the Pin1-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
Pathways
- Amoebiasis
- Axon guidance
- Bacterial invasion of epithelial cells
- Chemical carcinogenesis reactive oxygen species
- Chemokine signaling pathway
- Endocrine resistance
- ErbB signaling pathway
- Fluid shear stress and atherosclerosis
- Focal adhesion
- Growth hormone synthesis, secretion and action
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Human papillomavirus infection
- Leukocyte transendothelial migration
- Lipid and atherosclerosis
- PI3K Akt signaling pathway
- Pathways in cancer
- Proteoglycans in cancer
- Regulation of actin cytoskeleton
- Shigellosis
- Small cell lung cancer
- Transcriptional misregulation in cancer
- VEGF signaling pathway
- Yersinia infection
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement