| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI001965 | P05412 JUN JUN_HUMAN |
60 | 65 | LRAKNSDLLTSPDVGLLKLA | TP | --- | Homo sapiens (Human) | 331 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Wulf,2001 | support | certain | |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Wulf,2001 | support | certain | InteractionDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Wulf,2001 | support | certain | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q13526) PIN1_HUMAN | PF00397
(WW)
WW domain |
7 | 37 | [mitab][xml] |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000040:
Phosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
Pathways
- AGE RAGE signaling pathway in diabetic complications
- Amphetamine addiction
- Apoptosis
- B cell receptor signaling pathway
- Breast cancer
- C type lectin receptor signaling pathway
- Chagas disease
- Chemical carcinogenesis reactive oxygen species
- Chemical carcinogenesis receptor activation
- Choline metabolism in cancer
- Cocaine addiction
- Colorectal cancer
- Coronavirus disease COVID 19
- Endocrine resistance
- Epithelial cell signaling in Helicobacter pylori infection
- Epstein Barr virus infection
- ErbB signaling pathway
- Estrogen signaling pathway
- Fluid shear stress and atherosclerosis
- Focal adhesion
- GnRH signaling pathway
- Hepatitis B
- Human T cell leukemia virus 1 infection
- Human immunodeficiency virus 1 infection
- IL 17 signaling pathway
- Inflammatory bowel disease
- Kaposi sarcoma associated herpesvirus infection
- Leishmaniasis
- Lipid and atherosclerosis
- MAPK signaling pathway
- Measles
- Mitophagy animal
- NOD like receptor signaling pathway
- Neurotrophin signaling pathway
- Non alcoholic fatty liver disease
- Osteoclast differentiation
- Oxytocin signaling pathway
- PD L1 expression and PD 1 checkpoint pathway in cancer
- Pathogenic Escherichia coli infection
- Pathways in cancer
- Pertussis
- Relaxin signaling pathway
- Renal cell carcinoma
- Rheumatoid arthritis
- Salmonella infection
- Shigellosis
- T cell receptor signaling pathway
- TNF signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Tight junction
- Toll like receptor signaling pathway
- Viral carcinogenesis
- Wnt signaling pathway
- Yersinia infection
- cAMP signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement