Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI001943 | P38936 CDKN1A CDN1A_HUMAN |
145 | 157 | RRQTSMTDFYHSKRRLIFSK | TP | --- | Homo sapiens (Human) | 164 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0051 | fluorescence technology | Nishitani,2008 | support | certain | InteractionDetection | |
experimental | MI:0256 | rna interference | in vivo | Nishitani,2008 | support | certain | InteractionDetection |
experimental | MI:0997 | ubiquitinase assay | in vitro | Nishitani,2008 | support | certain | InteractionDetection |
experimental | MI:0113 | western blot | in vitro | Nishitani,2008 | support | certain | ParticipantIdentification FeatureDetection |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Nishitani,2008 | support | certain | InteractionDetection |
experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Nishitani,2008 | support | certain | FeatureDetection |
experimental | MI:0256 | rna interference | in vivo | Abbas,2008 | support | certain | InteractionDetection |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Abbas,2008 | support | certain | InteractionDetection |
experimental | MI:0997 | ubiquitinase assay | in vitro | Abbas,2008 | support | certain | InteractionDetection |
experimental | MI:0007 | anti tag coimmunoprecipitation | in vivo | Abbas,2008 | support | certain | InteractionDetection |
experimental | MI:0113 | western blot | in vitro | Abbas,2008 | support | certain | ParticipantIdentification FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q9NZJ0) DTL_HUMAN | PF00400
(WD40)
WD domain, G-beta repeat |
[mitab][xml] | |||
(P12004) PCNA_HUMAN | PF02747
(PCNA_C)
Proliferating cell nuclear antigen, C-terminal domain |
127 | 254 | [mitab][xml] |
Pathways
KEGG: The sequence P38936 is implicated in the following 41 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Basal cell carcinoma
- Bladder cancer
- Breast cancer
- Cell cycle
- Cellular senescence
- Chronic myeloid leukemia
- Colorectal cancer
- Cushing syndrome
- Endocrine resistance
- Endometrial cancer
- Epstein Barr virus infection
- ErbB signaling pathway
- FoxO signaling pathway
- Gastric cancer
- Glioma
- HIF 1 signaling pathway
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human papillomavirus infection
- JAK STAT signaling pathway
- Kaposi sarcoma associated herpesvirus infection
- Melanoma
- MicroRNAs in cancer
- Non small cell lung cancer
- Oxytocin signaling pathway
- PI3K Akt signaling pathway
- Pancreatic cancer
- Parathyroid hormone synthesis, secretion and action
- Pathways in cancer
- Platinum drug resistance
- Prostate cancer
- Proteoglycans in cancer
- Renal cell carcinoma
- Small cell lung cancer
- Thyroid cancer
- Transcriptional misregulation in cancer
- Viral carcinogenesis
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement