The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001938 P46527 CDKN1B
CDN1B_HUMAN
183 190 GSPNAGSVEQTPKKPGLRRR TP 2AST  
pdb:2AST
Homo sapiens (Human) 198

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0997 ubiquitinase assay in vitro Hao,2005 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Hao,2005 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Hao,2005 support certain InteractionDetection FeatureDetection

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P46527 is implicated in the following 19 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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