The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001696 P23385 Grm1
GRM1_RAT
1152 1156 EDSPALTPPSPFRDSVASGS TP --- Rattus norvegicus (Norway rat) 1199

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Beneken,2000 support certain
predicted MI:0114 x-ray crystallography in vitro Tu,1998 support certain InteractionDetection FeatureDetection
experimental MI:0113 western blot in vitro Beneken,2000 support certain ParticipantIdentification FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Beneken,2000 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9Z214) HOME1_RAT PF00568 (WH1)
WH1 domain
1 107 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P23385 is implicated in the following 13 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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