The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001607 Q99700 ATXN2
ATX2_HUMAN
912 924 VRKSTLNPNAKEFNPRSFSQ TP 3KTR  
pdb:3KTR
Homo sapiens (Human) 1313

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Lim,2006 support likely InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Lim,2006 support likely InteractionDetection FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Lim,2006 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Lim,2006 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Kozlov,2010 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P11940) PABP1_HUMAN PF00658 (PABP)
Poly-adenylate binding protein, unique domain
543 614 0.68/0.76 [mitab][xml]
(Q62671) UBR5_RAT PF00658 (PABP)
Poly-adenylate binding protein, unique domain
499 571 9.9/9.9 [mitab][xml]

o  Pathways

KEGG: The sequence Q99700 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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