ELM - instance LIG_PAM2_1 in sequence Q8IYD1 at position 50

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI001605	Q8IYD1 GSPT2 ERF3B_HUMAN	50	62	AFSRKLNVNAKPFVPNVHAA	TP	3KUI	Homo sapiens (Human)	628

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0107	surface plasmon resonance	in vitro	Kozlov,2004	support	not specified	InteractionDetection FeatureDetection
experimental	MI:0065	isothermal titration calorimetry	in vitro	Kozlov,2004	support	not specified	InteractionDetection
experimental	MI:0019	coimmunoprecipitation	in vivo/in vitro	Funakoshi,2007	support	not specified	InteractionDetection
experimental	MI:0107	surface plasmon resonance	in vitro	Lim,2006	support	not specified	InteractionDetection FeatureDetection
experimental	MI:0065	isothermal titration calorimetry	in vitro	Lim,2006	support	not specified	InteractionDetection
experimental	MI:0107	surface plasmon resonance	in vitro	Kozlov,2004	support	likely	InteractionDetection FeatureDetection
experimental	MI:0114	x-ray crystallography	in vitro	Kozlov,2010	support	certain	InteractionDetection FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P11940) PABP1_HUMAN	PF00658 (PABP) Poly-adenylate binding protein, unique domain	543	614	1.6/1.6	[mitab][xml]
(Q62671) UBR5_RAT	PF00658 (PABP) Poly-adenylate binding protein, unique domain	499	571	5.2/5.2	[mitab][xml]

Pathways

KEGG: The sequence Q8IYD1 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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