The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001604 Q9H074 PAIP1
PAIP1_HUMAN
126 138 VLMSKLSVNAPEFYPSGYSS TP 1JH4  
pdb:1JH4
Homo sapiens (Human) 479

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Roy,2002 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Kozlov,2004 support certain
experimental MI:0065 isothermal titration calorimetry in vitro Lim,2006 support likely InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Lim,2006 support likely InteractionDetection FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Kozlov,2004 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Kozlov,2004 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Kozlov,2004 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Roy,2002 support certain FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Roy,2002 support certain InteractionDetection FeatureDetection
experimental MI:0047 far western blotting in vitro Roy,2002 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Roy,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P11940) PABP1_HUMAN PF00658 (PABP)
Poly-adenylate binding protein, unique domain
543 614 1.5/2.3 [mitab][xml]
(Q62671) UBR5_RAT PF00658 (PABP)
Poly-adenylate binding protein, unique domain
499 571 3.4/3.4 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org