The Eukaryotic Linear Motif resource for
Functional Sites in Proteins
LIG_PAM2_1

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001602 Q9BPZ3 PAIP2
PAIP2_HUMAN 		109 121 VVKSNLNPNAKEFVPGVKYG TP 1JGN  
pdb:1JGN 3KUS  
pdb:3KUS 3KUT  
pdb:3KUT 		Homo sapiens (Human) 127

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Kozlov,2004 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Yoshida,2006 support likely InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Yoshida,2006 support likely InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Yoshida,2006 support likely InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Yoshida,2006 support likely InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Kozlov,2004 support certain FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Kozlov,2004 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Kozlov,2004 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Kozlov,2004 support certain InteractionDetection FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Kozlov,2010 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Kozlov,2010 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P11940) PABP1_HUMAN PF00658 (PABP)
Poly-adenylate binding protein, unique domain 		543 614 0.16/0.35 [mitab][xml]
(O95071) UBR5_HUMAN PF00658 (PABP)
Poly-adenylate binding protein, unique domain 		2376 2449 6.0/8.8 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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