The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001587 P04626 ERBB2
ERBB2_HUMAN
1250 1255 TFKGTPTAENPEYLGLDVPV TP 1MFG  
pdb:1MFG 1MFL  
pdb:1MFL
Homo sapiens (Human) 1255

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Birrane,2003 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Birrane,2003 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q96RT1) LAP2_HUMAN PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
1321 1407 [mitab][xml]

o  Pathways

KEGG: The sequence P04626 is implicated in the following 22 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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