Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI001587 | P04626 ERBB2 ERBB2_HUMAN |
1250 | 1255 | TFKGTPTAENPEYLGLDVPV | TP |
1MFG 1MFL |
Homo sapiens (Human) | 1255 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Birrane,2003 | support | certain | InteractionDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Birrane,2003 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q96RT1) LAP2_HUMAN | PF00595
(PDZ)
PDZ domain (Also known as DHR or GLGF) |
1321 | 1407 | [mitab][xml] |
Pathways
KEGG: The sequence P04626 is implicated in the following 22 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Adherens junction
- Bladder cancer
- Breast cancer
- Calcium signaling pathway
- Central carbon metabolism in cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocrine resistance
- Endometrial cancer
- ErbB signaling pathway
- Focal adhesion
- Gastric cancer
- HIF 1 signaling pathway
- MAPK signaling pathway
- MicroRNAs in cancer
- Non small cell lung cancer
- PI3K Akt signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Platinum drug resistance
- Prostate cancer
- Proteoglycans in cancer
- Tight junction
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement