The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001566 P16109 SELP
LYAM3_HUMAN
820 827 PHSHLGTYGVFTNAAFDPSP TP --- Homo sapiens (Human) 830

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0018 two hybrid in vivo Schluter,2009 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Schluter,2009 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P49757) NUMB_HUMAN PF00640 (PID)
Phosphotyrosine interaction domain (PTB/PID)
39 172 [mitab][xml]

o  Pathways

KEGG: The sequence P16109 is implicated in the following 6 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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