| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length | 
|---|---|---|---|---|---|---|---|---|
| ELMI001443 |  Q07889 SOS1 SOS1_HUMAN  | 
        1175 | 1181 | SKIMSKHLDSPPAIPPRQPT | TP | --- | Homo sapiens (Human) | 1333 | 
  Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes | 
|---|---|---|---|---|---|---|---|
| experimental | MI:0068 | mass detection of residue modification | in vitro | Corbalan-Garcia,1996 | support | certain | FeatureDetection | 
| experimental | MI:0424 | protein kinase assay | in vitro | Corbalan-Garcia,1996 | support | certain | InteractionDetection | 
| experimental | MI:0424 | protein kinase assay | in vivo | Corbalan-Garcia,1996 | support | certain | InteractionDetection | 
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Corbalan-Garcia,1996 | support | certain | FeatureDetection | 
  Pathways 
- Acute myeloid leukemia
 - Alcoholism
 - B cell receptor signaling pathway
 - Breast cancer
 - Chemical carcinogenesis reactive oxygen species
 - Chemical carcinogenesis receptor activation
 - Chemokine signaling pathway
 - Choline metabolism in cancer
 - Chronic myeloid leukemia
 - Colorectal cancer
 - EGFR tyrosine kinase inhibitor resistance
 - Endocrine resistance
 - Endometrial cancer
 - ErbB signaling pathway
 - Estrogen signaling pathway
 - Fc epsilon RI signaling pathway
 - Focal adhesion
 - FoxO signaling pathway
 - Gap junction
 - Gastric cancer
 - Glioma
 - GnRH signaling pathway
 - Growth hormone synthesis, secretion and action
 - Hepatitis B
 - Hepatitis C
 - Hepatocellular carcinoma
 - Human cytomegalovirus infection
 - Human papillomavirus infection
 - Insulin signaling pathway
 - JAK STAT signaling pathway
 - MAPK signaling pathway
 - MicroRNAs in cancer
 - Natural killer cell mediated cytotoxicity
 - Neurotrophin signaling pathway
 - Non small cell lung cancer
 - PI3K Akt signaling pathway
 - Pathways in cancer
 - Phospholipase D signaling pathway
 - Prolactin signaling pathway
 - Prostate cancer
 - Proteoglycans in cancer
 - Ras signaling pathway
 - Regulation of actin cytoskeleton
 - Relaxin signaling pathway
 - Renal cell carcinoma
 - T cell receptor signaling pathway
 - Thermogenesis
 - mTOR signaling pathway
 
    
        Please cite: 
            ELM-the Eukaryotic Linear Motif resource-2024 update.
        
    (PMID:37962385)
    
    
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
