Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI001315 | P05923 vpu VPU_HV1BR |
51 | 56 | RLIERAEDSGNESEGEISAL | TP | --- | Human immunodeficiency virus type 1 (BRU ISOLATE) | 81 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0077 | nuclear magnetic resonance | in vitro | Coadou,2003 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0517 | radiolabel | in vitro | Besnard-Guerin,2004 | support | certain | |
experimental | MI:0663 | confocal microscopy | in vivo/in vitro | Besnard-Guerin,2004 | support | certain | InteractionDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000159:
Dual phosphorylation of S52 and S56 in the TrCP1-binding motif of Protein Vpu (vpu) targets the protein to the SCF ubiquitin ligase complex, which marks it for degradation.
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement