| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI001315 | P05923 vpu VPU_HV1BR |
51 | 56 | RLIERAEDSGNESEGEISAL | TP | --- | Human immunodeficiency virus type 1 (BRU ISOLATE) | 81 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0077 | nuclear magnetic resonance | in vitro | Coadou,2003 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0517 | radiolabel | in vitro | Besnard-Guerin,2004 | support | certain | |
| experimental | MI:0663 | confocal microscopy | in vivo/in vitro | Besnard-Guerin,2004 | support | certain | InteractionDetection |
Switches
This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
-
SWTI000159:
Dual phosphorylation of S52 and S56 in the TrCP1-binding motif of Protein Vpu (vpu) targets the protein to the SCF ubiquitin ligase complex, which marks it for degradation.
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement