Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI000805 | P08581 MET MET_HUMAN |
1356 | 1359 | HYVHVNATYVNVKCVAPYPS | TP |
1FYR |
Homo sapiens (Human) | 1390 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0114 | x-ray crystallography | in vitro | Schiering,2000 | support | certain | InteractionDetection FeatureDetection |
not annotated | not specified | Palka,2003 | not specified | not specified |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P62993) GRB2_HUMAN | PF00017
(SH2)
SH2 domain |
60 | 135 | [mitab][xml] |
Pathways
KEGG: The sequence P08581 is implicated in the following 23 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Adherens junction
- Axon guidance
- Bacterial invasion of epithelial cells
- Calcium signaling pathway
- Central carbon metabolism in cancer
- Chemical carcinogenesis reactive oxygen species
- EGFR tyrosine kinase inhibitor resistance
- Epithelial cell signaling in Helicobacter pylori infection
- Focal adhesion
- Gastric cancer
- Hepatocellular carcinoma
- MAPK signaling pathway
- Malaria
- Melanoma
- MicroRNAs in cancer
- Non small cell lung cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Proteoglycans in cancer
- Rap1 signaling pathway
- Ras signaling pathway
- Renal cell carcinoma
- Transcriptional misregulation in cancer
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement