| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI000016 | P25942 CD40 TNR5_HUMAN |
231 | 239 | APHPKQEPQEINFPDDLPGS | TP |
1LB6 |
Homo sapiens (Human) | 277 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Ye,2002 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Ye,2002 | support | certain | FeatureDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Ye,2002 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Pullen,1999 | support | certain | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q9Y4K3) TRAF6_HUMAN | IPR037309
(TNF receptor-associated factor 6, MATH domain)
TNF receptor-associated factor 6 (TRAF6) regulates a diverse array of processes, including adaptive immunity, innate immunity, bone metabolism and tissue development |
351 | 500 | 84.0/84.0 | [mitab][xml] |
Pathways
- Allograft rejection
- Asthma
- Autoimmune thyroid disease
- Cell adhesion molecules
- Cytokine cytokine receptor interaction
- Epstein Barr virus infection
- Human T cell leukemia virus 1 infection
- Intestinal immune network for IgA production
- Lipid and atherosclerosis
- Malaria
- NF kappa B signaling pathway
- Primary immunodeficiency
- Systemic lupus erythematosus
- Toll like receptor signaling pathway
- Toxoplasmosis
- Transcriptional misregulation in cancer
- Viral myocarditis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement