The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

Pathways linked from ELM instances

The following list contains those pathways annotated at the "Kyoto Encyclopedia of Genes and Genomes" (KEGG) database for which at least one sequence is stored in the ELM database (containing at least one ELM instance). Sequences have been mapped from Uniprot to KEGG and colored in the pathway according to a simple colorscheme.

TaxonPathway entryPathway name# Instances# Sequences
mmu05221 Acute myeloid leukemia 2 2
mmu04520 Adherens junction 3 3
mmu04920 Adipocytokine signaling pathway 4 4
mmu04261 Adrenergic signaling in cardiomyocytes 3 2
mmu05034 Alcoholism 4 4
mmu05330 Allograft rejection 1 1
mmu05010 Alzheimer's disease 2 2
mmu05146 Amoebiasis 2 2
mmu05031 Amphetamine addiction 3 3
mmu04152 AMPK signaling pathway 6 6
mmu04612 Antigen processing and presentation 2 2
mmu04210 Apoptosis 1 1
mmu05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 3 2
mmu05310 Asthma 1 1
mmu05320 Autoimmune thyroid disease 1 1
mmu04360 Axon guidance 5 5
mmu05100 Bacterial invasion of epithelial cells 3 3
mmu05217 Basal cell carcinoma 4 4
mmu04662 B cell receptor signaling pathway 8 8
mmu04976 Bile secretion 1 1
mmu05219 Bladder cancer 1 1
mmu04020 Calcium signaling pathway 1 1
mmu04024 cAMP signaling pathway 4 4
mmu04260 Cardiac muscle contraction 2 1
mmu04514 Cell adhesion molecules (CAMs) 3 3
mmu04110 Cell cycle 6 5
mmu05230 Central carbon metabolism in cancer 1 1
mmu04022 cGMP PKG signaling pathway 1 1
mmu05142 Chagas disease (American trypanosomiasis) 6 5
mmu04062 Chemokine signaling pathway 7 7
mmu05231 Choline metabolism in cancer 4 4
mmu04725 Cholinergic synapse 3 3
mmu05220 Chronic myeloid leukemia 3 3
mmu04713 Circadian entrainment 4 4
mmu04710 Circadian rhythm 2 2
mmu05030 Cocaine addiction 2 2
mmu05210 Colorectal cancer 5 5
mmu04060 Cytokine cytokine receptor interaction 3 3
mmu04623 Cytosolic DNA sensing pathway 1 1
mmu05414 Dilated cardiomyopathy 3 2
mmu04728 Dopaminergic synapse 4 4
mmu04320 Dorso ventral axis formation 1 1
mmu04512 ECM receptor interaction 2 2
mmu04961 Endocrine and other factor regulated calcium reabsorption 1 1
mmu04144 Endocytosis 10 10
mmu05213 Endometrial cancer 4 4
mmu05169 Epstein Barr virus infection 7 7
mmu04012 ErbB signaling pathway 5 5
mmu04915 Estrogen signaling pathway 6 6
mmu03460 Fanconi anemia pathway 1 1
mmu04664 Fc epsilon RI signaling pathway 6 6
mmu04666 Fc gamma R mediated phagocytosis 3 3
mmu04510 Focal adhesion 8 8
mmu04068 FoxO signaling pathway 5 5
mmu04727 GABAergic synapse 1 1
mmu04540 Gap junction 2 2
mmu04971 Gastric acid secretion 1 1
mmu05214 Glioma 2 2
mmu04922 Glucagon signaling pathway 2 2
mmu04724 Glutamatergic synapse 2 2
mmu00604 Glycosphingolipid biosynthesis ganglio series 1 1
mmu00563 Glycosylphosphatidylinositol(GPI) anchor biosynthesis 1 1
mmu04912 GnRH signaling pathway 3 3
mmu04340 Hedgehog signaling pathway 4 4
mmu04640 Hematopoietic cell lineage 3 2
mmu05161 Hepatitis B 5 5
mmu05160 Hepatitis C 2 2
mmu05168 Herpes simplex infection 4 4
mmu04390 Hippo signaling pathway 8 7
mmu05166 HTLV I infection 14 13
mmu05016 Huntington's disease 1 1
mmu05410 Hypertrophic cardiomyopathy (HCM) 2 1
mmu05321 Inflammatory bowel disease (IBD) 1 1
mmu04750 Inflammatory mediator regulation of TRP channels 1 1
mmu05164 Influenza A 4 4
mmu04911 Insulin secretion 1 1
mmu04910 Insulin signaling pathway 4 4
mmu04672 Intestinal immune network for IgA production 1 1
mmu04630 Jak STAT signaling pathway 3 3
mmu05134 Legionellosis 1 1
mmu05140 Leishmaniasis 2 2
mmu04670 Leukocyte transendothelial migration 3 3
mmu04730 Long term depression 1 1
mmu04720 Long term potentiation 2 2
mmu04142 Lysosome 1 1
mmu05144 Malaria 2 2
mmu04010 MAPK signaling pathway 12 11
mmu04950 Maturity onset diabetes of the young 1 1
mmu05162 Measles 8 7
mmu04916 Melanogenesis 6 6
mmu05218 Melanoma 1 1
mmu01100 Metabolic pathways 3 3
mmu05206 MicroRNAs in cancer 6 6
mmu05032 Morphine addiction 3 3
mmu03015 mRNA surveillance pathway 1 1
mmu04150 mTOR signaling pathway 2 2
mmu04650 Natural killer cell mediated cytotoxicity 5 5
mmu04080 Neuroactive ligand receptor interaction 1 1
mmu04722 Neurotrophin signaling pathway 5 5
mmu04064 NF kappa B signaling pathway 5 5
mmu04621 NOD like receptor signaling pathway 1 1
mmu04932 Non alcoholic fatty liver disease (NAFLD) 3 3
mmu03450 Non homologous end joining 1 1
mmu05223 Non small cell lung cancer 2 2
mmu04330 Notch signaling pathway 2 2
mmu04740 Olfactory transduction 3 3
mmu04114 Oocyte meiosis 3 3
mmu04380 Osteoclast differentiation 9 9
mmu04913 Ovarian steroidogenesis 1 1
mmu04921 Oxytocin signaling pathway 6 5
mmu04115 p53 signaling pathway 2 2
mmu05212 Pancreatic cancer 1 1
mmu04972 Pancreatic secretion 1 1
mmu05012 Parkinson's disease 1 1
mmu05200 Pathways in cancer 16 16
mmu05133 Pertussis 2 2
mmu04145 Phagosome 1 1
mmu04744 Phototransduction 2 2
mmu04151 PI3K Akt signaling pathway 12 12
mmu04611 Platelet activation 5 5
mmu03320 PPAR signaling pathway 1 1
mmu05340 Primary immunodeficiency 4 4
mmu05020 Prion diseases 2 2
mmu04914 Progesterone mediated oocyte maturation 3 3
mmu04917 Prolactin signaling pathway 5 5
mmu05215 Prostate cancer 6 6
mmu04141 Protein processing in endoplasmic reticulum 5 4
mmu05205 Proteoglycans in cancer 9 9
mmu04015 Rap1 signaling pathway 3 3
mmu04014 Ras signaling pathway 7 6
mmu04810 Regulation of actin cytoskeleton 4 4
mmu04923 Regulation of lipolysis in adipocytes 1 1
mmu05211 Renal cell carcinoma 2 2
mmu04614 Renin angiotensin system 1 1
mmu04924 Renin secretion 2 2
mmu04723 Retrograde endocannabinoid signaling 1 1
mmu05323 Rheumatoid arthritis 3 3
mmu00740 Riboflavin metabolism 1 1
mmu03018 RNA degradation 1 1
mmu03013 RNA transport 1 1
mmu04970 Salivary secretion 2 2
mmu05132 Salmonella infection 4 4
mmu04726 Serotonergic synapse 2 2
mmu04550 Signaling pathways regulating pluripotency of stem cells 8 6
mmu05222 Small cell lung cancer 3 3
mmu04071 Sphingolipid signaling pathway 1 1
mmu03040 Spliceosome 2 2
mmu05322 Systemic lupus erythematosus 2 2
mmu04742 Taste transduction 1 1
mmu04660 T cell receptor signaling pathway 11 10
mmu05216 Thyroid cancer 4 4
mmu04919 Thyroid hormone signaling pathway 5 5
mmu04918 Thyroid hormone synthesis 1 1
mmu04530 Tight junction 1 1
mmu04668 TNF signaling pathway 3 3
mmu04620 Toll like receptor signaling pathway 3 3
mmu05145 Toxoplasmosis 2 2
mmu05202 Transcriptional misregulation in cancer 4 4
mmu05152 Tuberculosis 2 1
mmu04930 Type II diabetes mellitus 1 1
mmu00350 Tyrosine metabolism 1 1
mmu04270 Vascular smooth muscle contraction 1 1
mmu04962 Vasopressin regulated water reabsorption 2 2
mmu04370 VEGF signaling pathway 1 1
mmu05203 Viral carcinogenesis 7 7
mmu05416 Viral myocarditis 4 4
mmu04310 Wnt signaling pathway 6 6
Links redirect to the KEGG database with a color overlay corresponding to ELM classes.

Coloring is as follows:
CLV (cleavage site)
DOC (docking site)
DEG (degradation motif)
LIG (ligand binding motif)
MOD (modification site)
TRG (targeting motif)
multiple classes per sequence
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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