ELMThe Eukaryote Linear Motif resource for Functional Sites in  Proteins
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o ELM related links
ELM associated databases
  • Phospho.ELM - The Phospho.ELM database contains a collection of experimentally verified Serine, Threonine and Tyrosine sites in metazoan proteins
Other general motif resources
  • PROSITE - Database of protein families and domains (includes patterns describing some functional sites)
  • HPRD - The Human Protein Reference Database
Specialised motif resources
  • PepCyber - Phosphopeptide-binding domain resource
  • NetPhos - Prediction of phosphorylation sites
  • Scansite - Searches for phosphorylation sites and motifs that bind to domains such as SH2, 14-3-3 or PDZ .
  • iSPOT - Prediction of interaction with protein domains (SH3, PDZ, WW...)
  • O-GlycBase - Database of O- and C-glycosylated proteins
  • NetOGlyc - Predictions of mucin type GalNAc O-glycosylation sites in mammalian proteins
  • YinOYang - predictions for O-beta-GlcNAc attachment sites in eukaryotic protein sequences
  • NetNGlyc - Predicts N-Glycosylation sites in human proteins
  • PredictNLS - Prediction and analysis of nuclear localization signals
  • The Sulfinator - Predicts tyrosine sulfation sites in protein sequences
  • NMT - prediction of N-terminal N-myristoylation of proteins
  • big-PI - GPI Modification Site Prediction
  • DGPI - Detection/prediction of GPI cleavage site (GPI-anchor) in a protein
  • RESID - Database of annotations and structures for protein modifications
  • DeltaMass - Mass database of protein post translational modifications
  • PSORT - Predicts protein sorting signals and localization sites in amino acid sequences
  • TargetP - Prediction of subcellular location
  • SignalP - Prediction of cleavage sites and signal peptide/non-signal peptide prediction
  • ChloroP - Predicts the presence of chloroplast transit peptides
  • MITOPROT - Prediction of mitochondrial targeting sequences
  • Predotar - A prediction service for identifying putative mitochondrial and plastid targeting sequences
 
Many of these links were collected from ExPASy and Amos' WWW links.



o Protein interaction links
  • STRING - proteins and their interactions
  • MINT - Molecular interaction database
  • IntAct - Interaction database
  • MPact - Yeast interaction resource
  • DIP - Database of interacting proteins
  • ProNet - Protein interactions
 

o Motif discovery and search tools
  • SIRW - Combines the ability to search protein databases with keywords and a sequence motif
  • ScanProsite - Scan a protein sequence for the occurrence of patterns or search protein databases with a user-entered pattern
  • PATTINPROT - Scan a protein database or sequence for a pattern
  • Swiss Shop - Service that allows you to automatically obtain (by email) new sequence entries by pattern matching.
  • Pratt - Pattern discovery
  • eMOTIF - Motif discovery and searching
  • Teiresias - Sequence pattern discovery
  • FPAT - Regular expression searches of sequence databases
  • DILIMOT - Explore interaction data for linear motif candidates
  • SLIMFinder - Explore interaction data for linear motif candidates
  • Glam2 - Motif finding software
 



o Protein architecture links
  • SWISS-PROT - A curated protein sequence database
  • InterPro - Provides an integrated view of the commonly used signature databases (domains and functional sites)
  • SMART - Protein domain prediction (HMMs) and annotation
  • Pfam - Protein families database of alignments and HMMs
  • ProDom - Protein domain database (automatically generated)
  • GlobPlot - Discover protein sequence disorder and globularity
  • DisEMBL - Predictors of protein disorder
  • Blocks - Databsae of multiply aligned ungapped segments corresponding to the most highly conserved regions of proteins
  • PRINTS - Protein fingerprints database
  • PredictProtein - Structure prediction and sequence analysis
  • TMHMM - Prediction of transmembrane helices in proteins
  • TMpred - Prediction of transmembrane regions and orientation
  • IUPRED - predict native disorder/IUP
  • RONN - predict native disorder/IUP
  • DisPROT - IUP resource with native disorder DB, predictors and more
 



o Other interesting links
  • GO - Gene Ontology - dynamic controlled vocabulary for gene and protein roles in cells
  • GOtcha - Predict function (GO terms) of proteins
  • SRS - Sequence Retreival System
  • UTOPIA/CINEMA - Annotated alignment visualisation tool
  • JalView - Annotated alignment visualisation tool
 

Last modified 05-FEB-2008 - webmaster