The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003571 Q5T4F4 ZFYVE27
ZFY27_HUMAN
285 293 EAEPDEEFKDAIEETHLVVL TP --- Homo sapiens (Human) 411

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0405 competition binding in vitro Saita,2009 support likely InteractionDetection
experimental MI:0943 detection by mass spectrometry in vivo/in vitro Saita,2009 support likely InteractionDetection
experimental MI:0663 confocal microscopy in vivo/in vitro Saita,2009 support certain InteractionDetection
experimental MI:0113 western blot in vitro Saita,2009 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Saita,2009 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Saita,2009 support certain FeatureDetection
experimental MI:0663 confocal microscopy in vivo/in vitro Saita,2009 support likely InteractionDetection
experimental MI:0113 western blot in vitro Saita,2009 support likely ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Saita,2009 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9P0L0) VAPA_HUMAN PF00635 (Motile_Sperm)
MSP (Major sperm protein) domain
14 120 [mitab][xml]
(O95292) VAPB_HUMAN PF00635 (Motile_Sperm)
MSP (Major sperm protein) domain
7 113 [mitab][xml]

o  Pathways

KEGG: The sequence Q5T4F4 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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