The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003567 P22059 OSBP
OSBP1_HUMAN
356 364 SDEDDENEFFDAPEIITMPE TP 2RR3  
Homo sapiens (Human) 807

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Furuita,2010 support likely FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Furuita,2010 support likely InteractionDetection FeatureDetection
experimental MI:0519 glutathione s tranferase tag in vitro Wyles,2004 support likely
experimental MI:0096 pull down in vivo/in vitro Wyles,2004 support likely InteractionDetection
experimental MI:0017 classical fluorescence spectroscopy in vitro Loewen,2003 support certain InteractionDetection
experimental MI:0367 green fluorescent protein tag in vivo Loewen,2003 support certain
experimental MI:0519 glutathione s tranferase tag in vitro Loewen,2003 support certain
experimental MI:0096 pull down in vivo/in vitro Loewen,2003 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Loewen,2003 support certain FeatureDetection
experimental MI:0367 green fluorescent protein tag in vivo Loewen,2003 support likely
experimental MI:0663 confocal microscopy in vivo/in vitro Loewen,2003 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Loewen,2003 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q6Q595) SCS22_YEAST PF00635 (Motile_Sperm)
MSP (Major sperm protein) domain
1 106 4.0/6.0 [mitab][xml]
(Q9P0L0) VAPA_HUMAN PF00635 (Motile_Sperm)
MSP (Major sperm protein) domain
14 120 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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