| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI004293 | P01730 CD4 CD4_HUMAN |
434 | 439 | RQAERMSQIKRLLSEKKTCQ | TP |
2JKR |
Homo sapiens (Human) | 458 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0107 | surface plasmon resonance | in vitro | Kelly,2008 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Kelly,2008 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:2286 | functional association | in vivo/in vitro | Pitcher,1999 | support | likely | InteractionDetection ParticipantIdentification |
| experimental | MI:1088 | phenotype-based detection assay | Pitcher,1999 | support | likely | InteractionDetection | |
| experimental | MI:0517 | radiolabel | in vitro | Pitcher,1999 | support | likely | |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Pitcher,1999 | support | likely | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P62743) AP2S1_MOUSE | PF01217
(Clat_adaptor_s)
Clathrin adaptor complex small chain |
1 | 142 | [mitab][xml] |
Pathways
- Antigen processing and presentation
- Cell adhesion molecules
- Cytokine cytokine receptor interaction
- Hematopoietic cell lineage
- Human T cell leukemia virus 1 infection
- Human immunodeficiency virus 1 infection
- PD L1 expression and PD 1 checkpoint pathway in cancer
- Primary immunodeficiency
- T cell receptor signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Yersinia infection
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement