The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004293 P01730 CD4
CD4_HUMAN
434 439 RQAERMSQIKRLLSEKKTCQ TP 2JKR  
Homo sapiens (Human) 458

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0107 surface plasmon resonance in vitro Kelly,2008 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Kelly,2008 support certain InteractionDetection FeatureDetection
experimental MI:2286 functional association in vivo/in vitro Pitcher,1999 support likely InteractionDetection ParticipantIdentification
experimental MI:1088 phenotype-based detection assay Pitcher,1999 support likely InteractionDetection
experimental MI:0517 radiolabel in vitro Pitcher,1999 support likely
experimental MI:0074 mutation analysis in vivo/in vitro Pitcher,1999 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P62743) AP2S1_MOUSE PF01217 (Clat_adaptor_s)
Clathrin adaptor complex small chain
1 142 [mitab][xml]

o  Pathways

KEGG: The sequence P01730 is implicated in the following 12 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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