| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003361 | O14920 IKBKB IKKB_HUMAN |
747 | 753 | LDWSWLQTEEEEHSCLEQAS | TP | --- | Homo sapiens (Human) | 756 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Higashimoto,2008 | support | certain | FeatureDetection |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Higashimoto,2008 | support | certain | |
| experimental | MI:0424 | protein kinase assay | in vitro | Higashimoto,2008 | support | certain | InteractionDetection |
Switches
This ELM instance is part of the following 3 switching mechanisms annotated at the switches.ELM resource:
-
LEVEL:
None
-
LOW:
None
-
PHOSPHORYLATION:
None
Pathways
- Acute myeloid leukemia
- Adipocytokine signaling pathway
- Alzheimer disease
- Antifolate resistance
- Apoptosis
- B cell receptor signaling pathway
- C type lectin receptor signaling pathway
- Chagas disease
- Chemical carcinogenesis reactive oxygen species
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Coronavirus disease COVID 19
- Cytosolic DNA sensing pathway
- Epithelial cell signaling in Helicobacter pylori infection
- Epstein Barr virus infection
- Fluid shear stress and atherosclerosis
- FoxO signaling pathway
- Hepatitis B
- Hepatitis C
- Herpes simplex virus 1 infection
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Human papillomavirus infection
- IL 17 signaling pathway
- Influenza A
- Insulin resistance
- Insulin signaling pathway
- Kaposi sarcoma associated herpesvirus infection
- Lipid and atherosclerosis
- MAPK signaling pathway
- Measles
- MicroRNAs in cancer
- NF kappa B signaling pathway
- NOD like receptor signaling pathway
- Neurotrophin signaling pathway
- Non alcoholic fatty liver disease
- Osteoclast differentiation
- PD L1 expression and PD 1 checkpoint pathway in cancer
- PI3K Akt signaling pathway
- Pancreatic cancer
- Pathogenic Escherichia coli infection
- Pathways in cancer
- Prostate cancer
- RIG I like receptor signaling pathway
- Ras signaling pathway
- Salmonella infection
- Shigellosis
- Small cell lung cancer
- T cell receptor signaling pathway
- TNF signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Toll like receptor signaling pathway
- Toxoplasmosis
- Type II diabetes mellitus
- Yersinia infection
- mTOR signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement