Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI002425 | P46527 CDKN1B CDN1B_HUMAN |
152 | 160 | QCAGIRKRPATDDSSTQNKR | TP | --- | Homo sapiens (Human) | 198 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0424 | protein kinase assay | in vivo/in vitro | Shin,2002 | support | certain | InteractionDetection |
experimental | MI:0424 | protein kinase assay | in vitro | Shin,2002 | support | certain | InteractionDetection |
experimental | MI:0424 | protein kinase assay | in vivo | Shin,2002 | support | certain | InteractionDetection |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Shin,2002 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Shin,2002 | support | certain | FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P31749) AKT1_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
150 | 408 | [mitab][xml] |
Pathways
KEGG: The sequence P46527 is implicated in the following 19 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- Cell cycle
- Chronic myeloid leukemia
- Cushing syndrome
- Endocrine resistance
- Epstein Barr virus infection
- ErbB signaling pathway
- FoxO signaling pathway
- Gastric cancer
- HIF 1 signaling pathway
- Human papillomavirus infection
- Measles
- MicroRNAs in cancer
- PI3K Akt signaling pathway
- Pathways in cancer
- Prostate cancer
- Small cell lung cancer
- Transcriptional misregulation in cancer
- Viral carcinogenesis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement