The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002553 P04049 RAF1
RAF1_HUMAN
254 262 GSLSQRQRSTSTPNVHMVST TP --- Homo sapiens (Human) 648

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0424 protein kinase assay in vitro Wang,2008 support likely InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Wang,2008 support likely InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P31749) AKT1_HUMAN PF00069 (Pkinase)
Protein kinase domain
150 408 [mitab][xml]

o  Pathways

The sequence P04049 is implicated in the following 54 Pathways: (color codes: This sequence=red, interacting sequence=orange)

o  Diseases

Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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