The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000123 P04275 VWF
1147 1149 GYECEWRYNSCAPACQVTCQ TP --- Homo sapiens (Human) 2813

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0570 protein cleavage in vivo/in vitro Titani,1986 support certain

o  Pathways

KEGG: The sequence P04275 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)

o  Diseases

  • Sequence Variation VAR_064925 (Pos 1149) has been implicated in Von Willebrand Disease, Type 1; Vwd1 (OMIM:193400).
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement