The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004609 P46150 Moe
MOEH_DROME
556 561 NVRQGRDKYKTLREIRKGNT TP --- Drosophila melanogaster (Fruit fly) 578

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Hughes,2006 support certain InteractionDetection
experimental MI:1088 phenotype-based detection assay Hipfner,2004 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Hipfner,2004 support certain InteractionDetection
experimental MI:0858 immunodepleted coimmunoprecipitation in vitro Hipfner,2004 support certain InteractionDetection
experimental MI:0788 knock out in vivo Hipfner,2004 support certain
experimental MI:0403 colocalization in vitro Hipfner,2004 support certain
experimental MI:0113 western blot in vitro Kunda,2008 support certain ParticipantIdentification FeatureDetection
experimental MI:0256 rna interference in vivo Kunda,2008 support certain InteractionDetection
experimental MI:1088 phenotype-based detection assay Carreno,2008 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Carreno,2008 support certain
experimental MI:0403 colocalization in vitro Carreno,2008 support certain
experimental MI:0256 rna interference in vivo Carreno,2008 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q8MLP1) Q8MLP1_DROME IPR000719 (Protein kinase domain)
Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases
37 295 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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