The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002176 P84022 SMAD3
SMAD3_HUMAN
201 208 QMNHSMDAGSPNLSPNPMSP TP --- Homo sapiens (Human) 425

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0788 knock out in vivo Wang,2009 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Wang,2009 support certain FeatureDetection
experimental MI:0424 protein kinase assay in vitro Wang,2009 support certain InteractionDetection

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P84022 is implicated in the following 16 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org